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Causes and Risk Factors

Sciatica results from inflammation, irritation, or compression of the sciatic nerve or nerve root (i.e., base of the nerve at the spinal cord). The most common cause for sciatica is intervertebral disc damage in the lumbar or sacral region of the spine (i.e., the lower back).

The spine or backbone is comprised of 33 bone segments called vertebrae. Vertebrae are arranged in a vertical column and held together by ligaments, which are attached to muscles by tendons. ...Read the full article